疏肝导浊方干预家兔肝脏脂肪变的实验研究 |
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作者:陈嵘 海青山 许力跃 尧雪洲 雷娟 杨榆青
【摘要】 目的:观察疏肝导浊方对家兔实验性肝脏脂肪变的干预作用。方法:42只家兔随机分为正常组、模型组、疏肝导浊方低、中、高剂量组和饮食Methods:Forty-two rabbits were ran into 4 groups.Normal group was breed common forage.Model group was breed high lipoid forage.Shugandaozhuo complex prescription group was intragastric administered with Chinese materia medica after 12-week high lipoid forage(including 3 subgroups with different dosis).Placebo group was breed common forage after 12-week high lipoid forage.The model group were sacrificed 12 weeks later and other groups were killed 16 weeks later.Blood samples were harvested before putting to death and liver tissue samples were harvested for histological examination.The levels of total cholesterol(TC),triglyceride(TG),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),alanine aminotransferase(ALT) and aspartate aminotransferase [1] [2] [3] 下一页 |
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