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PLC delta1基因在上皮性卵巢肿瘤中的表达和临床意义 |
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| PLC delta1基因在上皮性卵巢肿瘤中的表达和临床意义 |
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conducted to reveal the relationship between PLC delta 1 expression and the occurrence of epithelial ovarian cancer. 【Results】 Among 197 valid samples， most of the borderline tumor cases (25 samples， 80.6%) indicated normal expression of PLC delta 1; most of the ovarian cancer cases (91 samples， 54.8%)， on the other hand， indicated overexpression of PLC delta 1. The study also found a significant difference in PLC delta 1 expression (P < 0.000 1) between the two types of cases. Also， there is a significant correlation between the PLC delta 1 expression in the ovarian cancer cases and their clinical stages， as well as the age of the patients (P < 0.000 1). 【Conclusion】 The overexpression of PLC delta 1 in the ovarian cancer tissue is closely related to tumor malignancy， suggesting that PLC delta 1 could be another effective marker for the diagnosis of ovarian cancer.
卵巢癌是女性生殖器官常见恶性肿瘤，发病年龄以50岁左右为高峰。由于卵巢肿瘤发病隐匿，早期诊断困难，大多数(约70%)卵巢癌患者在初诊时已是浸润晚期(FIGOⅢ或Ⅳ期)的肿瘤，其5年生存率不超过30%，死亡率居 上一页 [1] [2] [3] [4] [5] [6] [7] [8] [9] 下一页 |
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