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作者：王仲略 沈惠琳 周刚 李之印
【摘要】 ［目的］比较艾迪注射液辅助选择性动脉插管化疗治疗（治疗组）与单用选择性动脉插管化疗治疗（对照组）对中晚期胃癌的临床疗效。［方法］选择中晚期胃癌患者56例随机分为两组，治疗组予FAM方案选择性的动脉插管化疗同时加用艾迪注射液,对照组予FAM方案选择性的动脉插管化疗，比较艾迪辅助组和非艾迪辅助组的近期疗效、临床症状、生存质量、不良反应的差异。［结果］治疗组在改善患者生活质量、保护化疗后骨髓功能方面明显优于对照组,差异有统计学意义,P<0.05,且无明显不良反应,对肿瘤疗效两组差异无统计学意义。［结论］艾迪注射液与选择性动脉插管化疗联合应用,疗效显著,可改善患者的生存质量。
【关键词】 胃癌; 艾迪注射液;插管化疗；生存质量
Abstract: ［objective］ To evaluate the effects of Aidiinjection to assist selective arterial infusion chemotherapy for advanced gastric cancer.［Methods］56 cases with advanced gastric cancer of TNM stage Ⅱ to Ⅲ were randomly divided into two groups.Treatment group(30 cases) received FAM regimen via selective arterial infusion chemotherapy, chemoembolization and Aidiinjection, control group(26 cases) received FAM regimen via selective arterial infusion chemotherapy and chemoembolization.Alleviation and metastasis，clinical symptoms, quality of life and side effects were compared between two groups.［Result］ Aidiinjection reduced the sideeffect of chemotherapy, improved physical status(PS) and regulated immunologic function.There was no difference about tumor effective rate between the two groups.［Conclusion］Aideiinjection in combination with seletive infusion chemothevapy has amrked cure effect and can improve life quality.
Key words: gastric cancer;Aidiinjection;arterial infusion chemotherapy;quality of life
我院自2002年1月至2006年12月，对30例晚期胃癌患者采用艾迪注射液加FAM方案选择性胃动脉插管灌注化疗栓塞治疗，并于同期26例单用选择性动脉插管化疗治疗晚期胃癌作临床疗效对照分析，进行了观察比较，现报告如下。
1 资料与方法
1.1 一般资料 56例均为我院消化科住院病人，均经胃镜及病理确诊为胃癌，化疗前均经CT或B超确诊为胃癌晚期，56例患者随机分为治疗组30例，男19例，女11例，年龄35～78岁，平均55岁。对照组26例，男17例，女9例，年龄35～85岁，平均57岁。TMN分期，11例为Ⅲ期，15例为Ⅳ期。
1.2 治疗方法 治疗组采用Seldinger法将6号导管置于腹腔干动脉 [1] [2] 下一页 |
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