| 网站首页 | 范文 | 演讲致词 | 汇报体会 | 总结报告 | 公文方案 | 领导讲话 | 党建工会 | 论文 | 文档 | 
您现在的位置: 范文大全网 >> 论文 >> 免费范文 >> 正文 用户登录 新用户注册
硬膜外应用虎纹镇痛肽I对自体神经移植大鼠脊髓背角cfos表达的影响           
硬膜外应用虎纹镇痛肽I对自体神经移植大鼠脊髓背角cfos表达的影响

【摘要】    目的 通过观察硬膜外给予虎纹镇痛肽I对大鼠自体神经移植模型机械痛阈与脊髓背角cfos表达的影响,探讨虎纹镇痛肽I对再生神经神经性疼痛的影响。方法 雄性Wistar大鼠60只随机分成A、B、C组,A组为自体神经移植模型组;B组为自体神经移植模型加虎纹镇痛肽I治疗组;C组为假手术组。分别制成模型后,术后27 d起检测机械刺激阈值及cfos表达计数。结果 A、B组各项指标与C组比较有显著差异;A组与B组比较cfos表达阳性细胞计数及机械痛阈均有显著差异。结论虎纹镇痛肽I能有效减轻再生神经的神经性疼痛程度,促进神经的完善修复。

【关键词】  周围神经损伤;神经再生;神经性疼痛;cfos;虎纹镇痛肽I

    Abstract: Objectives  To investigate the influence of huwena analegesic peptideI  (HWAPI) on neuropathic pain of the regeneration nerve by observing the machinery pain threshold and cfos expression in sciatic nerve autograft rat model after applying HWAPI epidurally. Methods  Totally 60 male Wistar rats were randomly divided into three groups: sciatic nerve autograft group (group A), sciatic nerve autograft with treatment of HWAPI group (group B) and sham group (group C). The machinery pain threshold and cfos expression were measured 27 days after the operation. Results&n

[1] [2] [3] [4] [5] [6] [7] 下一页

  • 上一个论文:

  • 下一个论文:
  • 推荐文章
    小剂量咪唑安定辅助硬膜外麻
    浅谈硬膜外麻醉下剖宫产手术
    经胸膜外病灶清除带蒂肋骨椎
    硬膜外冲击联合牵引推拿治疗
    硬膜外冲击联合牵引推拿治疗