| 入肝门静脉动脉化加门腔分流术对大鼠肝脏再生的影响 |
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associated with portocaval shunt (PCS) on liver regeneration after 70% partial hepatectomy (PH) in a rat model. 【Methods】 One hundred and fifty-five Sprague Dawley rats were assigned to three groups： PVA associated with PCS after 70% PH (experimental group); 70% PH only (PH group); right nephrectomy (control group). Liver regeneration rate (LRR) was assessed on days 2， 7， 14， and 28 after surgery， proliferating cell nuclear antigen (PCNA) labeling index， and S phase liver cell rate were assessed on 0 h， 24 h， 48 h， 72 h， and 7 days after surgery， respectively. 【Results】 Rats with 70% PH following PVA + PCS showed significantly greater liver growth than rats with 70% PH only in the first 14 days postoperatively (P < 0.01). However， no significant difference was found 28 days after surgery between these two groups. The rats with PVA + PCS showed the highest values of PCNA labeling index and S phase liver cell rates within 7 days， and higher than the other two non-PVA groups significan 上一页 [1] [2] [3] [4] [5] [6] [7] [8] [9] 下一页 |
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