| 针刺阳陵泉和非穴的fMRI脑功能成像研究 |
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作者：黄泳，黄璐，赖新生，邹燕齐，吴俊贤
【摘要】 ：［目的］探讨针刺阳陵泉穴对脑的激活效应。［方法］16例健康志愿者，随机分为阳陵泉穴组和非穴组，分别针刺右侧阳陵泉穴和非穴；同时，运用GE 1.5T超导核磁共振系统完成脑部fMRI扫描，所得数据采用感兴趣区（ROI）法进行处理和分析。［结果］针刺阳陵泉穴和针刺非穴对各脑区的激活几率没有显著性差异，针刺非穴对于双侧顶叶、左侧枕叶的激活点数量较针刺阳陵泉为多（P＜0.05），针刺非穴对于左侧小脑的激活强度大于针刺阳陵泉穴（P＜0.05）。［结论］针刺阳陵泉和非穴对于脑部功能区的激活方面有着一定的差异。
【关键词】 阳陵泉穴；非穴；fMRI；脑功能成像
Abstract: ［Objective］To observe the cerebral activating effects of needling in Yanglingquan (GB34) vs a sham point of healthy volunteers based on the technique of fMRI.［Methods］Sixteen healthy volunteers were randomly divided into GB34 group and sham point group，and received needling in the different points on the right side respectfully.Super nuclear magnetic resonance (1.5T，GE Co.) was used to scan the brain and the obtained experimental data of the regional brain were processed and analyzed by method of Region of Interest (ROI).［Results］There was not any difference between needling in GB34 and the sham point in the cerebral activating rate.While the activating number of needling in the sham point was more than that of needling in GB34 in bilateral parietal lobes and right occipital lobe（P＜0.05），and the activating strength of needling in the sham point was stronger than that of needling in GB34 in left cerebellum（P＜0.05）.［Conclusion］Needling in GB34 and the sham point had a certain degree of difference in the activation of cerebral functional regions.
Key words：Yanglingquan(GB34)；sham point；fMRI；cerebral functional imaging
穴位特异性的研究，包括了穴位和非穴的比较。研究中，通常在穴位旁开处定位一个“非穴”，用该非穴与穴位进行比较［12］。本研究在上肢前臂外侧定位一个“非穴”，将其用于与位于下肢膝关节附近的、足少阳胆经的阳陵泉穴比较。本研究采用功能性磁共振成像技术（fMRI）比较针刺阳陵泉穴与该非穴对不同脑部功能区的激活，总结如下。
1 临床资料
16例健康志愿者，来自广州各大高校，均符合以下纳入标准：（1）年龄21～28岁在校学生（非医学专业），身体健康，男女各半；（2）饮食规律，不嗜烟酒茶咖啡等，睡眠正常，体型适中；（3）实 [1] [2] [3] 下一页 |
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