雌二醇鼻腔喷雾剂大鼠体内的药动学研究 |
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rves in rats nasally administered with estradiol nasal spray at the doses of 0. 16, 0.48, and 1.60 mg·kg-1
图2 雌二醇环糊精包合物溶液鼻腔给药后大鼠体内血药浓度时间关系曲线图(给药剂量:0.16 mg·kg-1)(略)
Figure 2 Plasma concentrationtime curves in rats nasally administered with estradiolRAMEB solution at the dose of 0.16 mg·kg-1
图3 雌二醇乙醇溶液鼻腔给药后大鼠体内血药浓度时间关系曲线图(给药剂量:0.16 mg·kg-1)(略)
Figure 3 Plasma concentrationtime curves in rats nasally administered with estradiolethanol solution at the dose of 0.16 mg·kg-1
图4 静脉注射雌二醇溶液后大鼠体内血药浓度时间关系曲线图(给药剂量:0. 16 mg·kg-1)(略) Figure 4 Plasma concentrationtime curves in rats intravenously injected with estradiolethanol solution at the dose of 0.16 mg·kg-1
表1 鼻腔给药后各制剂的主要药动学参数(略)
Table 1 Pharmacokinetic parameter 上一页 [1] [2] [3] [4] [5] [6] [7] [8] [9] 下一页 |
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